Mabapi le MedGence
MedGence ke e 'ngoe ea lik'hamphani tsa bohlokoa tsa meriana ea tlhaho tsa CRO naheng ea China.Re khethehile ho etsa lipatlisiso tsa meriana ea tlhaho le motsoako.Re fana ka lits'ebeletso tse felletseng ho tloha tlhahlobong ea thepa e tala ho isa phepelong ea lihlahisoa tsa ho qetela lefapheng la meriana ea tlhaho.Ho tloha ha re theoa lilemo tse 14 tse fetileng, esale re fana ka lits'ebeletso tsa R&D bakeng sa bahlahisi le lipetlele tse fetang 100 tse etelletseng pele tsa meriana Chaena.Re qetile lithuto tsa sejoale-joale tsa bongaka tsa liforomo tse 83 tsa Classic Traditional Chinese Medicine, ra etsa litlhare tsa tlhaho tse 22 tse ncha, ra fumana ngoliso ea meriana e lokiselitsoeng sepetlele e 56, le ho theha litekanyetso le mekhoa ea tlhahiso ea meriana e ka bang 400 ea litlama tse le 'ngoe.Re bokelletse likete tse makholo tsa li-batch tsa lintlha tsa lipatlisiso mabapi le lisebelisoa tsa tlhaho tse tsoang, litlama tsa TCM, le litokisetso tsa bongaka.Litšebeletso tsa rona li kenyelletsa ho ntlafatsa tlhahiso ea li-supplement tsa lijo, ho hlahisa lintho tsa phytochemical e le lithethefatsi tse ncha tse tšepisang, ho fumana tharollo e ncha ea litlolo, joalo-joalo Re boetse re fana ka tšebeletso ea CDMO bakeng sa tsohle tse ka holimo.
Seo re se Etsang
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Ho hlahloba motsoako o sebetsang oa limela
Limela tsa tlhaho li na le palo e kholo ea metsoako e sebetsang, e kang alkaloids, polysaccharides, saponins, joalo-joalo Lintho tsena tse sebetsang li ka sebelisoa meriana, tlhokomelo ea bophelo, litlolo le chefo e bolaeang likokoanyana le lihlahisoa tse ling.Ha moreki a batla motsoako oa tlhaho bakeng sa ts'ebeliso e itseng, re ka fana ka thuso.Ho ipapisitsoe le pokello ea rona e pharalletseng ea data le bokhoni bo matla ba tlhahlobo, re ka thusa moreki oa rona ho lekola le ho tseba hore na ke lintho life tse sebetsang hantle ho fihlela phello e itseng le hore na limela li na le (li) metsoako e lakatsehang ka bongata bo boholo, e le ho fana ka tharollo ka bobeli ho nahanoa ka moruo le botsoalle tikoloho. -
Boithuto le tlhahlobo ea matla a motsoako o sebetsang oa botanical ho tloha linakong tse fapaneng tsa selemo le litloholo tse fapaneng.
Limela tse tšoanang tse melang libakeng tse fapaneng li ka ba le phapang e kholo matleng a metsoako e sebetsang.Esita le haeba limela tse hōlang sebakeng se le seng li tla ba le phapang ea matla a metsoako e sebetsang ho tloha linakong tse fapaneng.Ka lehlakoreng le leng, boemo bo fapaneng ba limela bo fapane ka matla a metsoako e sebetsang.Mosebetsi oa rona o thusa bareki ba rona ho tseba sebaka se setle ka ho fetisisa sa tšimoloho, nako ea kotulo e nepahetseng ka ho fetisisa le likarolo tse sebetsang ka ho fetisisa tsa thepa e tala, kahoo e thusa bareki ba rona ho haha tharollo e sebetsang hantle le e ntle ka ho fetisisa ea ho fumana chelete. -
Ho theha mekhoa ea tlhahlobo ea motsoako (li)
Mokhoa o netefalitsoeng oa tlhahlobo ke ntlha ea bohlokoa ho netefatsa ntho e sebetsang.Mekhoa ea tlhahlobo eo re e etselitseng moreki oa rona e ka netefatsa hore moreki oa rona o na le lisebelisoa tse tšepahalang tsa ho laola boleng mme kahoo a fumana tšepo ho tsoa 'marakeng.Ho ipapisitsoe le sehlahisoa, mekhoa ea tlhahlobo e amehang e tla kenyelletsa tsohle kapa tse ling tsa tse latelang: chromatography ea lera le tšesaane e sebetsang hantle haholo (HPTLC), chromatography ea metsi e sebetsang hantle haholo (HPLC), chromatography ea khase (GC), chromatography ea menoana, jj. . -
Boithuto ba tšebetso ea tlhahiso bakeng sa(li)sebetsi
Ha motsoako o sebetsang o notletsoe, ke habohlokoa haholo ho sebetsa ka mokhoa oa ho o hlahisa ka theko e ntle ka ho fetisisa.Sehlopha sa rona se ka theha ts'ebetso e sebetsang ka ho fetisisa ea tlhahiso bakeng sa bareki ba rona ho matlafatsa tlholisano le ho fokotsa khatello ho tlhaho.Ts'ebeletso ea rona e kenyelletsa ho lokisa thepa e tala, mokhoa o tsoelang pele oa ts'ebetso (joalo ka tlhoekiso, ho tlosa, ho omisa, joalo-joalo).Lintlha tsa bohlokoa tse thathamisitsoeng ka holimo li ka ba bohlokoa haholo ho fumana katleho ea tlhahiso. -
Boithuto ba tšebetso ea tlhahiso bakeng sa lihlahisoa tse felileng
Ho ka ba le mathata a mang ha u ntse u fetola metsoako e sebetsang hore e be lihlahisoa tse sebelisoang.Mohlala, ts'ebetso e fosahetseng e ka fokotsa litaba tsa metsoako e sebetsang, kapa e ka ba le khaello ea solubility kapa tatso.Sehlopha sa rona se ka boela sa fana ka litšebeletso tsa lipatlisiso ho rarolla mathata a ka holimo bakeng sa bareki ba rona. -
Lithuto tsa chefo
Tšireletseho e tlameha ho netefatsoa pele sehlahisoa se hlahisoa 'marakeng.Re etsa lithuto tsa chefo lihlahisoa tsa bareki ba rona, ho ba imolla matšoenyehong, le ho fumana lihlahisoa tse sebetsang hantle le tse bolokehileng ho li rekisa.Ts'ebeletso e kenyelletsa boithuto bo matla ba chefo ea LD50, thuto ea chefo e sa foleng, thuto ea chefo ea lefutso, jj. -
Teko ea In Vitro
Teko ea in vitro e ka fana ka karabelo ea sele le litho ho motsoako(li)sebetsi, ho fana ka litšupiso ho lekola hore na thuto e lokela ho tsoela pele.Leha tlhahlobo ea in vitro e sa lokela ho ithuta ka lisebelisoa tsohle tse sebetsang, ntle le pelaelo ke ntlha ea bohlokoa e ka ts'ehetsang moreki oa rona ho etsa qeto ka litšenyehelo tse nyane haholo hobane tlhahlobo ea nako ea vitro e na le tšebeliso e tlase haholo ka litšenyehelo le nako.Mohlala, ha ho etsoa metsoako e sebetsang bakeng sa taolo ea tsoekere ea mali, kapa lihlahisoa tse thibelang kokoana-hloko, lintlha tse fumanoeng litekong tsa in vitro li na le moelelo. -
Thuto ea liphoofolo
Re fana ka litšebeletso tsa thuto ea liphoofolo bakeng sa bareki ba rona.Teko ea chefo le teko ea ho sebetsa mefuteng ea boithuto ba liphoofolo, hangata, e ka ba litšupiso tse molemo haholo bakeng sa lihlahisoa tsa bareki ba rona, haholo-holo bakeng sa litlolo tsa phepo le litlolo.Ho fapana le boithuto ba tleliniki, thuto ea liphoofolo ke mokhoa o potlakileng le o theko e tlaase oa teko ho netefatsa hore sehlahisoa se tla sebetsa hantle ebile se se kotsi. -
Thuto ea tleliniki
Tlas'a lipatlisiso tsa konteraka bakeng sa motsoako o mocha o sebetsang kapa foromo e ncha, re ka hlophisa boithuto ba tleliniki, ho latela tlhoko, ho kenyelletsa le tsela ea batho ka sehlopha se senyenyane bakeng sa li-supplement tsa lijo, hammoho le mohato oa I, phase II, phase III le phase IV thuto ea tleliniki e leng e hlokoang ke litlhoko tse ncha tsa kopo ea lithethefatsi, ho tšehetsa bareki ba rona ho fumana lintlha tse hlokahalang le ho tšoaneleha bakeng sa kopo e ncha ea lithethefatsi (NDA). -
Boithuto ba tlhaho ea tlhaho
Ho ipapisitsoe le bokello ba rona lefapheng la liphuputso tsa Traditional Chinese Medicine (TCM), re sebetsa ka mokhoa o ikhethileng ka metsoako ea tlhaho, ho ntlafatsa ts'ebetso ea li-supplement tsa lijo le kapa ho hlahisa meriana e mecha.Ts'ebeletso e ka ba ts'ebetso e felletseng e kenyelletsang litlhophiso, ho theha litekanyetso tsa thepa e tala, ho theha mekhoa ea tlhahlobo, ntlafatso ea ts'ebetso ea tlhahiso, boithuto ba katleho le boithuto ba chefo, joalo-joalo. Ho sa le joalo, mosebetsi o boletsoeng ka holimo o ka etsoa ka kopo. -
Tlhahiso ea konteraka (OEM) bakeng sa motsoako o sebetsang
Re ka hlophisa tlhahiso bakeng sa thepa e tala e boletsoeng eo moreki oa rona a neng a e lakatsa.Re na le polante ea rona ea liteko le lifeme tse sebelisanang tse tlas'a taolo e tobileng ea sehlopha sa rona sa tekheniki, liphetho tsohle tsa thuto li ka fetoloa hantle hore e be tlhahiso le ho netefatsa hore moreki oa rona a ka fumana sehlahisoa seo a se batlang sa boleng bo holimo ka nako e nepahetseng.Sebopeho sa motsoako o sebetsang e ka ba lino tse tahang, matla, li-pastes, oli e sa tsitsang, joalo-joalo. -
Tlhahiso ea konteraka (OEM) bakeng sa lihlahisoa tse felileng
Ka setsi sa rona sa liteko le lifeme tse sebelisanang, re ka fana ka nts'etsopele ea likonteraka le tšebeletso ea tlhahiso ea likonteraka (CDMO) bakeng sa bareki ba rona.Lihlahisoa tsa rona e ka ba lino tse tahang, li-capsules, li-softgels, matlapa, li-soluble powders, granules, joalo-joalo Ho itšetlehile ka semelo sa rona se khethehileng sa theknoloji le mohlala oa rona oa khoebo ea ho etsa likonteraka, re khona ho tiisa hore ho tsamaisoa ka nako, boleng bo ka tšeptjoang le ho se senole ha tsebo- Joang.
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Bareki ba rona
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China Beijing Tongrentang Group Co., Ltd.>
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China Resources Sanjiu Medical & Pharmaceutical Co., Ltd.>
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Beihai Gofar Chuanshan Biological Co., Ltd.>
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Humanwell Healthcare (Sehlopha) Co., Ltd.>
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SCIMYTH Pharmaceutical Group>
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Shandong Hanfang Pharmaceutical Co., Ltd.>
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Luoxin Pharmaceutical Group Stock Co., Ltd.>
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Guangdong Zhongsheng Pharmaceutical Co., Ltd.>
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Hunan Heng Chang Pharmaceutical Group Co., Ltd.>
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Baotou Traditional Chinese Medicine Co., Ltd.>
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Hunan Tianjicaotang Pharmaceutical Co., Ltd.>
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Jiangxi Kingstone Unite Pharmaceutical Co., Ltd.>
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Sepetlele sa Shuguang se Keneng le Shanghai Chinese Medicine University>
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Sepetlele sa TCM se sebetsanang ka kotloloho le Setereke sa Hunan>
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Sepetlele sa Pele sa Hunan University of Chinese Medicine>
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Sepetlele sa Bobeli sa Xiangya sa Central South University>
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Sepetlele sa Bobeli sa Hunan University of Chinese Medicine (Hunan Chinese Medicine Hospital)>
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The Orthopedics of Traditional Chinese Medicine Zhuzhou City>
